IDH2R140Q-IN-2
IDH2R140Q-IN-2 is an orally active and potent IDH2R140Q inhibitor with an IC50 of 29 nM.IDH2R140Q-IN-2 possesses potential antitumour activity, reducing D2HG production in TF-1 cell lines carrying the IDH2R140Q mutation (IC50 of 10 nM) and inhibiting tumour tissue D2HG levels.IDH2R140Q-IN-2 is suitable for the study of acute myeloid leukaemia (AML) .
Product Specifications
CAS Number
2749568-16-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
484.4
Molecular Formula
C21H18F6N6O
Notes
Research use only, not for human use.
Receptor
Dehydrogenase
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS2100326-01 5x 96 Tests
Human Thy1 Cell Surface Antigen (Thy1) Antibody Pair Kit (with Standard)
Sign In for Pricing
View Details MBS2100326-02 5x 96 Tests + MBS2090685 (Ab Pairs Support Pack 1,5x 96 Tests)
Human Thy1 Cell Surface Antigen (Thy1) Antibody Pair Kit (with Standard)
Sign In for Pricing
View Details MBS2100326-03 10x 96 Tests
Human Thy1 Cell Surface Antigen (Thy1) Antibody Pair Kit (with Standard)
Sign In for Pricing
View Details MBS2100326-04 10x 96 Tests + MBS2090685 (Ab Pairs Support Pack 1, 10x 96 Tests)
Human Thy1 Cell Surface Antigen (Thy1) Antibody Pair Kit (with Standard)
Sign In for Pricing
View Details 110700W0-AAT 100 Tests
MFluor™ Red 780 Anti-human/ non-human primates/ mouse CD107a Antibody *H4A3*
Sign In for Pricing
View Details