IDH2R140Q-IN-2
IDH2R140Q-IN-2 is an orally active and potent IDH2R140Q inhibitor with an IC50 of 29 nM.IDH2R140Q-IN-2 possesses potential antitumour activity, reducing D2HG production in TF-1 cell lines carrying the IDH2R140Q mutation (IC50 of 10 nM) and inhibiting tumour tissue D2HG levels.IDH2R140Q-IN-2 is suitable for the study of acute myeloid leukaemia (AML) .
Product Specifications
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
484.4
Molecular Formula
C21H18F6N6O
Notes
Research use only, not for human use.
Receptor
Dehydrogenase
CAS Number
2749568-16-7
Available Sizes
Curated Selection
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