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PD-L1-IN-3

PD-L1-IN-3 (Compound 4a) functions as an inhibitor of the PD-1/PD-L1 axis, with an IC50 value of 4.97 nM for PD-L1 inhibition and an EC50 value of 2.70 μM for Jurkat T cell modulation. It antagonizes the PD-1/PD-L1 interaction by binding to the PD-L1 dimer, obstructing PD-1 signaling. This compound is utilized in research pertaining to lung cancer and melanoma .

Product Specifications

CAS Number

2953044-29-4

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

373.85

Molecular Formula

C19H15ClFN2OS

Notes

Research use only, not for human use.

Receptor

PD-1/PD-L1

Available Sizes

Frequently Asked Questions

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