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DNL343

DNL343 is a selective and potent eIF2B activator that crosses the blood-brain barrier and inhibits the assembly of stress granules (SGs) induced by the C9ORF72 dipeptide repeats. DNL343 may be useful in the study of neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS) .

Product Specifications

CAS Number

2278265-85-1

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

457.83

Molecular Formula

C20H19ClF3N3O4

Notes

Research use only, not for human use.

Receptor

PERK

Available Sizes

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