DNL343
DNL343 is a selective and potent eIF2B activator that crosses the blood-brain barrier and inhibits the assembly of stress granules (SGs) induced by the C9ORF72 dipeptide repeats. DNL343 may be useful in the study of neurodegenerative diseases, such as amyotrophic lateral sclerosis (ALS) .
Product Specifications
CAS Number
2278265-85-1
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
457.83
Molecular Formula
C20H19ClF3N3O4
Notes
Research use only, not for human use.
Receptor
PERK
Available Sizes
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