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Nrf2-IN-3

Nrf2-IN-3 is a mKEAP1-selective NRF2 inhibitor that selectively binds KEAP1 mutants and restores their NRF2 inhibitory function by repairing the disrupted KEAP1/NRF2 interaction, and selectively sensitizes cisplatin in xenografts of mouse mKEAP1 cancer cells.

Product Specifications

CAS Number

6325-13-9

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

442.53

Molecular Formula

C22H26N4O4S

Notes

Research use only, not for human use.

Receptor

Nrf2

Available Sizes

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