Cixutumumab
Cixutumumab (IMC-A12), a humanized monoclonal antibody targeting IGF-1R, exhibits high affinity and inhibits ligand-dependent receptor activation, impeding downstream signaling. Additionally, it facilitates the internalization and degradation of IGF-1R. Demonstrating extensive antitumor efficacy, it is relevant in cancer research, including lung and prostate cancers, malignancies, and leukemia .
Product Specifications
CAS Number
947687-12-9
Stability
≥ 2 years
Purity
>98% (HPLC)
Molecular Formula
——
Notes
Research use only, not for human use.
Receptor
Others
Available Sizes
Curated Selection
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