JC2-11
JC2-11 is an inhibitory compound for inflammation.JC2-11 inhibits the recruitment domain-containing proteins NLRC 4, atypical in melanoma 2 (AIM 2) and atypical (NC) inflammatory vesicles by disrupting reactive oxygen species (ROS) production and caspase-1 activity.JC2-11 reduces caspase-1 (p20) secretion, gasdermin D (GSDMD) cleavage, IL-1β and lactate dehydrogenase (LDH) activity in inflammatory vesicles. JC2-11 reduced caspase-1 (p20) secretion, gasdermin D (GSDMD) cleavage, IL-1β and lactate dehydrogenase (LDH) release from inflammatory vesicles.
Product Specifications
CAS Number
937820-89-8
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
302.3
Molecular Formula
C17H15FO4
Notes
Research use only, not for human use.
Receptor
Dehydrogenase | IL Receptor | AIM2 | ROS | NOD-like Receptor (NLR) | Caspase
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
LHX1 (LIM Homeobox 1, LIM-1, LIM1, MGC126723, MGC138141) (HRP)
LHX1 (LIM Homeobox 1, LIM-1, LIM1, MGC126723, MGC138141) (HRP)
