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Petosemtamab

Petosemtamab (MCLA 158) is a highly potent monoclonal antibody against EGFR (Kd: 0.22 nM) and LGR5 (Kd: 0.86 nM) . Petosemtamab promotes EGFR signaling disruption and receptor breakdown in LGR5+ cancer cells. Petosemtamab can be used in the study of solid tumors such as head and neck squamous cell carcinoma (HNSCC) and metastatic colorectal cancer (CRC) .

Product Specifications

CAS Number

2213450-26-9

Stability

≥ 2 years

Purity

>98% (HPLC)

Molecular Formula

——

Notes

Research use only, not for human use.

Receptor

EGFR

Available Sizes

Frequently Asked Questions

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