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Conatumumab

Conatumumab (AMG 655) is a monoclonal agonist antibody targeting human death receptor 5 [DR5, TRAILR2] with a dissociation constant (Kd) of 1 nM for long DR5 and 0.8 nM for short DR5. It induces apoptosis in various tumor types through caspase activation and can be used to study advanced solid tumors.

Product Specifications

CAS Number

896731-82-1

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

145.65 (kDa)

Molecular Formula

——

Notes

Research use only, not for human use.

Receptor

TNF

Available Sizes

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