Conatumumab
Conatumumab (AMG 655) is a monoclonal agonist antibody targeting human death receptor 5 [DR5, TRAILR2] with a dissociation constant (Kd) of 1 nM for long DR5 and 0.8 nM for short DR5. It induces apoptosis in various tumor types through caspase activation and can be used to study advanced solid tumors.
Product Specifications
CAS Number
896731-82-1
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
145.65 (kDa)
Molecular Formula
——
Notes
Research use only, not for human use.
Receptor
TNF
Available Sizes
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