SLC26A3-IN-2
SLC26A3-IN-2 is an orally active compound that functions as an inhibitor of the anion exchanger protein SLC26A3, with an IC50 of 360 nM. This protein, a member of the solute carrier (SLC) family SLC26, has broad anion specificity including chloride, bicarbonate, sulfate, and oxalate. SLC26A3, also known as DRA, is typically down-regulated in adenoma and plays a crucial role in intestinal absorption of chloride and oxalate. Mutations causing loss of SLC26A3 function are associated with chloride-losing diarrhea .
Product Specifications
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
368.84
Molecular Formula
C19H13ClN2O2S
Notes
Research use only, not for human use.
Receptor
Others
CAS Number
950348-60-4
Available Sizes
Curated Selection
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