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Canakinumab

Canakinumab (ACZ885) is a recombinant human IL-1β-targeting monoclonal antibody that inhibits human and chorioallantoic monkey IL-1β with IC50 values of 43.6 and 40.8 pM, respectively. It exhibits anti-inflammatory activity by neutralizing IL-1β signaling, and it has been used for the treatment of gout and coronary artery disease.

Product Specifications

CAS Number

914613-48-2

Stability

≥ 2 years

Purity

>98% (HPLC)

Molecular Formula

——

Notes

Research use only, not for human use.

Receptor

IL Receptor

Available Sizes

Frequently Asked Questions

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