BPDA2
BPDA2 is a highly selective and competitive SHP2 inhibitor, exhibiting IC50 values of 92.0 nM for SHP2, and 33.39 μM and 40.71 μM for SHP1 and SHP1B, respectively. This compound effectively downregulates mitogenic and cell survival signaling, including reducing expression of receptor tyrosine kinases (RTKs) . Furthermore, BPDA2 suppresses SHP2-mediated signaling, leading to the inhibition of breast cancer cell phenotypes .
Product Specifications
CAS Number
2907659-86-1
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
398.49
Molecular Formula
C24H30O5
Notes
Research use only, not for human use.
Receptor
Phosphatase
Available Sizes
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