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LEM-14-1189 B

Lem-14-1189, a LEM-14 derivative, is a potent NSD inhibitor of the nuclear receptor binding SET domain, and has inhibitory effects on NSD1, NSD2, and NSD3, with IC50 of 418 μM, 111 μM, and 60 μM, respectively. LEM-14-1189 has potential anticancer activity and can be used to study multiple myeloma (MM) and diseases of the blood system.

Product Specifications

CAS Number

2987501-17-5

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

682.81

Molecular Formula

C35H34N6O5S2

Notes

Research use only, not for human use.

Receptor

Histone Methyltransferase

Available Sizes

Curated Selection

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