LEM-14-1189 B
Lem-14-1189, a LEM-14 derivative, is a potent NSD inhibitor of the nuclear receptor binding SET domain, and has inhibitory effects on NSD1, NSD2, and NSD3, with IC50 of 418 μM, 111 μM, and 60 μM, respectively. LEM-14-1189 has potential anticancer activity and can be used to study multiple myeloma (MM) and diseases of the blood system.
Product Specifications
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
682.81
Molecular Formula
C35H34N6O5S2
Notes
Research use only, not for human use.
Receptor
Histone Methyltransferase
CAS Number
2987501-17-5
Available Sizes
Curated Selection
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