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Darizmetinib

Darizmetinib (HRX215, HRX-0215) is an MKK4 inhibitor. Inhibition of MKK4 leads to enhancement of the MKK7 and JNK1 signaling pathways, thereby activating the transcription factors ATF2 and ELK1, promoting cell proliferation and liver regeneration.

Product Specifications

CAS Number

2369583-33-3

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

457.45

Molecular Formula

C21H17F2N5O3S

Notes

Research use only, not for human use.

Receptor

MAPK | Antiviral

Available Sizes

Curated Selection

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