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NMDAR/TRPM4-IN-2

NMDAR/TRPM4-IN-2 is a potent interfacial inhibitor of NMDAR/TRPM4 interaction.NMDAR/TRPM4-IN-2 protects against MCAO-induced brain damage and NMDA-induced retinal ganglion cell loss in mice.NMDAR/TRPM4-IN-2 has neuroprotective activity against NMDA-induced hippocampal neuronal cell death and mitochondrial dysfunction. NMDAR/TRPM4-IN-2 showed neuroprotective activity against NMDA-induced cell death and mitochondrial dysfunction in hippocampal neurons with an IC50 value of 2.1 μM.

Product Specifications

CAS Number

2243506-33-2

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

330.092

Molecular Formula

C11H19BrCl2N2

Notes

Research use only, not for human use.

Receptor

ERK | TRP/TRPV Channel | iGluR | NMDAR

Available Sizes

Curated Selection

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