FM04
FM04 is an orally active and highly potent inhibitor of P-glycoprotein (P-gp) with an EC50 value of 83 nM. FM04 can interact with Q1193 and I1115 in human P-gp nucleotide binding domain 2 (NBD2) . Thereby disrupting the R262-Q1081-Q1118 interaction pocket and uncoupling the ICL2-NBD2 interaction, thereby inhibiting P-gp. FM04 can be used in the treatment of cancer and tumors.
Product Specifications
CAS Number
1807320-40-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
415.48
Molecular Formula
C26H25NO4
Notes
Research use only, not for human use.
Receptor
P-gp
Available Sizes
Frequently Asked Questions
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