GTP-14564
GTP-14564 is a novel tyrosine kinase inhibitor that also inhibits wt-FLT3 and ITD-FLT3. GTP-14564 inhibits the growth of interleukin-3-independent Ba/F1 expressing ITD-FLT3 at 3 μ m, whereas a 30-fold higher concentration of GTP-14564 is required to inhibit the FLT3 ligand-dependent growth (wt-FLT3) of Ba/F3 expressing wild-type FLT3. F3 expressing wild-type FLT3 (wt-FLT3) .
Product Specifications
CAS Number
34823-86-4
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
234.25
Molecular Formula
C15H10N2O
Notes
Research use only, not for human use.
Receptor
Tyrosine Kinases | FLT
Available Sizes
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