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GTP-14564

GTP-14564 is a novel tyrosine kinase inhibitor that also inhibits wt-FLT3 and ITD-FLT3. GTP-14564 inhibits the growth of interleukin-3-independent Ba/F1 expressing ITD-FLT3 at 3 μ m, whereas a 30-fold higher concentration of GTP-14564 is required to inhibit the FLT3 ligand-dependent growth (wt-FLT3) of Ba/F3 expressing wild-type FLT3. F3 expressing wild-type FLT3 (wt-FLT3) .

Product Specifications

CAS Number

34823-86-4

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

234.25

Molecular Formula

C15H10N2O

Notes

Research use only, not for human use.

Receptor

Tyrosine Kinases | FLT

Available Sizes

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