HM90822
HM90822 is a novel synthetic apoptotic protein (IAP) antagonist that induces apoptosis in human pancreatic cancer cells through proteasome-dependent degradation of IAPs containing the BIR2/3 structural domain.HM90822 inhibits the expression of XIAP and cIAP1/2 proteins in HM822-sensitive Panc-1 and BxPC-3 cells, induces ubiquitylation of IAPs and promotes induces IAP ubiquitination and promotes proteasome-dependent IAP degradation.
Product Specifications
CAS Number
1363145-46-3
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
632.1
Molecular Formula
C30H36ClF2N7O4
Notes
Research use only, not for human use.
Receptor
IAP | Apoptosis
Available Sizes
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