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HM90822

HM90822 is a novel synthetic apoptotic protein (IAP) antagonist that induces apoptosis in human pancreatic cancer cells through proteasome-dependent degradation of IAPs containing the BIR2/3 structural domain.HM90822 inhibits the expression of XIAP and cIAP1/2 proteins in HM822-sensitive Panc-1 and BxPC-3 cells, induces ubiquitylation of IAPs and promotes induces IAP ubiquitination and promotes proteasome-dependent IAP degradation.

Product Specifications

CAS Number

1363145-46-3

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

632.1

Molecular Formula

C30H36ClF2N7O4

Notes

Research use only, not for human use.

Receptor

IAP | Apoptosis

Available Sizes

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