Pitavastatin
Pitavastatin (NK-104) is a potent inhibitor of hydroxymethylglutaryl-CoA (HMG-CoA) reductase, effectively inhibiting cholesterol synthesis from acetic acid in HepG2 cells with an IC50 of 5.8 nM. It also induces hepatocyte low-density lipoprotein-cholesterol (LDL-C) receptors and exhibits therapeutic activities such as anti-atherosclerotic, anti-asthmatic, anti-osteoarthritis, antineoplastic, neuroprotective, hepatoprotective, and reno-protective effects.
Product Specifications
CAS Number
147511-69-1
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
421.46
Molecular Formula
C25H24FNO4
Notes
Research use only, not for human use.
Receptor
Autophagy | HMG-CoA Reductase | Apoptosis | Mitophagy
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