Tebufelone
Tebufelone is a potent in vitro inhibitor of CO , a novel non-steroidal anti-inflammatory drug (NSAID) belonging to the di-tert-butylphenol (DTBP) class that has shown potent anti-inflammatory, analgesic and anti-reticulitis properties in various animal models. Tebufelone potently inhibits the formation of prostaglandins (PGE2) and blocks the formation of lipoxygenase pathway products [leukotriene (LTB4) ] in rat macrophages (IC50 = 20 microM) and human whole blood (IC50 = 22 microM) in vitro. = 20 microM) and human whole blood (IC50 = 22 microM) from the formation of lipoxygenase pathway products [leukotriene (LTB4) ] in vitro.
Product Specifications
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
300.44
Molecular Formula
C20H28O2
Notes
Research use only, not for human use.
Receptor
LTR | Prostaglandin Receptor
CAS Number
112018-00-5
Available Sizes
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