Butyzamide
Butyzamide is an effective and oral Mpl activator. It is a novel non-peptide-based molecule with antagonistic effects on thrombopoietin (TPO) receptors, which promotes proliferation of human Mpl (hMpl) expression and mouse pro B cell line Ba/F3. The phosphorylation of JAK2, STAT3, STAT5 and MAPK is induced. Butyzamide has been shown to help increase platelet levels in mouse xenotransplantation trials.
Product Specifications
CAS Number
1110767-45-7
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
591.55
Molecular Formula
C29H32Cl2N2O5S
Notes
Research use only, not for human use.
Receptor
Thrombopoietin Receptor | JAK
Available Sizes
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