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Butyzamide

Butyzamide is an effective and oral Mpl activator. It is a novel non-peptide-based molecule with antagonistic effects on thrombopoietin (TPO) receptors, which promotes proliferation of human Mpl (hMpl) expression and mouse pro B cell line Ba/F3. The phosphorylation of JAK2, STAT3, STAT5 and MAPK is induced. Butyzamide has been shown to help increase platelet levels in mouse xenotransplantation trials.

Product Specifications

CAS Number

1110767-45-7

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

591.55

Molecular Formula

C29H32Cl2N2O5S

Notes

Research use only, not for human use.

Receptor

Thrombopoietin Receptor | JAK

Available Sizes

Frequently Asked Questions

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