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USP8-IN-3

USP8-IN-3 is a potent inhibitor of the deubiquitinating enzymes USP7 and USP8, with IC50 of 4.0 μM against USP8D. USP8-IN-3 inhibited the proliferation of GH3 and H1957 cells with GI50 values of 37.03 μM and 6.01 μM, respectively. USP8-IN-3 is a potential compound for the treatment of cancer and viral infections.

Product Specifications

CAS Number

2477651-10-6

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

425.43

Molecular Formula

C18H18F3N5O2S

Notes

Research use only, not for human use.

Receptor

DUB

Available Sizes

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