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AT-533

AT-533 is a potent inhibitor of Hsp90 and HSV. AT-533 blocks the HIF-1α/VEGF/VEGFR-2 signaling pathway, leading to suppress tumor growth and angiogenesis. AT-533 also inhibits the activation of the downstream pathways, including Erk1/2, FAK, Akt/mTOR/p70S6K, . AT-533 inhibits the cell migration, invasion, and the tube formation of human umbilical vein endothelial cells (HUVECs) .

Product Specifications

CAS Number

908112-37-8

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

410.51

Molecular Formula

C23H30N4O3

Notes

Research use only, not for human use.

Receptor

HSP | HSV

Available Sizes

Curated Selection

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