AT-533
AT-533 is a potent inhibitor of Hsp90 and HSV. AT-533 blocks the HIF-1α/VEGF/VEGFR-2 signaling pathway, leading to suppress tumor growth and angiogenesis. AT-533 also inhibits the activation of the downstream pathways, including Erk1/2, FAK, Akt/mTOR/p70S6K, . AT-533 inhibits the cell migration, invasion, and the tube formation of human umbilical vein endothelial cells (HUVECs) .
Product Specifications
CAS Number
908112-37-8
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
410.51
Molecular Formula
C23H30N4O3
Notes
Research use only, not for human use.
Receptor
HSP | HSV
Available Sizes
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