BMS-903452
BMS-903452 is a potent and selective GPR119 agonist with an EC50 of 14 nM, indicated for the treatment of acute and chronic rodent diabetes. GPR119 is mainly expressed in pancreatic b cells and gastrointestinal endocrine cells. BMS-903452 shows no significant inhibitory effect on 9 cytochrome P450 enzymes (IC50 > 40 μM), does not activate PXR (EC50 > 50 μM), and is not toxic to liver (HEPG2) cell lines.
Product Specifications
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
513.37
Molecular Formula
C21H19Cl2FN4O4S
Notes
Research use only, not for human use.
Receptor
GPR
CAS Number
1339944-47-6
Available Sizes
Curated Selection
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