BMS-903452
BMS-903452 is a potent and selective GPR119 agonist with an EC50 of 14 nM, indicated for the treatment of acute and chronic rodent diabetes. GPR119 is mainly expressed in pancreatic b cells and gastrointestinal endocrine cells. BMS-903452 shows no significant inhibitory effect on 9 cytochrome P450 enzymes (IC50 > 40 μM), does not activate PXR (EC50 > 50 μM), and is not toxic to liver (HEPG2) cell lines.
Product Specifications
CAS Number
1339944-47-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
513.37
Molecular Formula
C21H19Cl2FN4O4S
Notes
Research use only, not for human use.
Receptor
GPR
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
T8266-86-APC 200 µL
Translocon-associated Protein Subunit alpha, NT (SSR1, TRAP-alpha, Signal Sequence Receptor Subunit alpha, SSR-alpha, SSR1, TRAPA, PSEC0262) (APC) discontinued
Ask
View Details 