Lomibuvir
Lomibuvir (VCH-222) is a selective, non-nucleoside allosteric inhibitor of HCV NS5B polymerase (RdRp) with a Kd of 17 nM. Lomibuvir inhibits the 1b/Con1 HCV subgenomic replicon with an EC 50 of 5.2 nM. Lomibuvir preferentially inhibits elongative RNA synthesis rather than de novo -initiated RNA synthesis .
Product Specifications
CAS Number
1026785-55-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
445.61
Molecular Formula
C25H35NO4S
Notes
Research use only, not for human use.
Receptor
HCV Protease
Available Sizes
Curated Selection
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