JI6
JI6 (JAK3 Inhibitor VI) is a potent, selective and orally active FLT3 inhibitor. JI6 exhibits IC50s of ∼40, 8, and 4 nM for FLT3-WT, FLT3-D835Y, and FLT3-D835H, respectively. JI6 also inhibits c-Kit and JAK3, with IC50s of ∼500 and ∼250 nM, respectively. JI6 has research value in acute myeloid leukemia.
Product Specifications
CAS Number
856436-16-3
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
383.42
Molecular Formula
C19H17N3O4S
Notes
Research use only, not for human use.
Receptor
FLT
Available Sizes
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