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JI6

JI6 (JAK3 Inhibitor VI) is a potent, selective and orally active FLT3 inhibitor. JI6 exhibits IC50s of ∼40, 8, and 4 nM for FLT3-WT, FLT3-D835Y, and FLT3-D835H, respectively. JI6 also inhibits c-Kit and JAK3, with IC50s of ∼500 and ∼250 nM, respectively. JI6 has research value in acute myeloid leukemia.

Product Specifications

CAS Number

856436-16-3

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

383.42

Molecular Formula

C19H17N3O4S

Notes

Research use only, not for human use.

Receptor

FLT

Available Sizes

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