20S Proteasome activator 1
20S Proteasome activator 1 is a 20S proteasome activator with IC50 values of 0.3 μM for trypsin-like sites, 0.7 μM for chymotrypsin-like sites, and 1.8 μM for caspase sites. It prevents the accumulation of pathogenic alpha-synuclein (A53T) mutants through translation in the cellular system, thereby reducing the probability of disease occurrence. 20S Proteasome activator 1 can be used to study neurodegenerative diseases.
Product Specifications
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
492.97
Molecular Formula
C27H19ClF2N2OS
Notes
Research use only, not for human use.
Receptor
Proteasome
CAS Number
2761578-18-9
Available Sizes
Curated Selection
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