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20S Proteasome activator 1

20S Proteasome activator 1 is a 20S proteasome activator with IC50 values of 0.3 μM for trypsin-like sites, 0.7 μM for chymotrypsin-like sites, and 1.8 μM for caspase sites. It prevents the accumulation of pathogenic alpha-synuclein (A53T) mutants through translation in the cellular system, thereby reducing the probability of disease occurrence. 20S Proteasome activator 1 can be used to study neurodegenerative diseases.

Product Specifications

CAS Number

2761578-18-9

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

492.97

Molecular Formula

C27H19ClF2N2OS

Notes

Research use only, not for human use.

Receptor

Proteasome

Available Sizes

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