Simmiparib
Simmiparib (SMOCL-9112) is a novel and potent PARP1 and PARP2 inhibitor, a derivative of Olaparib.Simmiparib induces DNA double-strand breaks (DSBs) and cell cycle arrest in homologous recombination repair (HR) -deficient cells, thereby contributing to apoptosis.Simmiparib has been used for study Parkinson's disease, Alzheimer's disease, breast cancer, and melanoma.
Product Specifications
CAS Number
1551355-46-4
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
486.42
Molecular Formula
C23H18F4N6O2
Notes
Research use only, not for human use.
Receptor
Apoptosis | PARP
Available Sizes
Curated Selection
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