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Simmiparib

Simmiparib (SMOCL-9112) is a novel and potent PARP1 and PARP2 inhibitor, a derivative of Olaparib.Simmiparib induces DNA double-strand breaks (DSBs) and cell cycle arrest in homologous recombination repair (HR) -deficient cells, thereby contributing to apoptosis.Simmiparib has been used for study Parkinson's disease, Alzheimer's disease, breast cancer, and melanoma.

Product Specifications

CAS Number

1551355-46-4

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

486.42

Molecular Formula

C23H18F4N6O2

Notes

Research use only, not for human use.

Receptor

Apoptosis | PARP

Available Sizes

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