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Osunprotafib

Osunprotafib (ABBV-CLS-484) is a potent, orally bioavailable PTP1B/PTPN2 inhibitor in clinical trials for solid tumors. Osunprotafib (ABBV-CLS-484) stimulates the tumor microenvironment and promotes natural killer cell and CD8 T cell function and enhances T cell anti-tumor immunity by enhancing JAK-STAT signaling and reducing T cell dysfunction.

Product Specifications

CAS Number

2489404-97-7

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

385.45

Molecular Formula

C17H24FN3O4S

Notes

Research use only, not for human use.

Receptor

Phosphatase

Available Sizes

Curated Selection

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