EM127
EM127 is a highly selective and potent covalent inhibitor of SMYD3 with a KD value of 13 μM.EM127 inhibits ERK1/2 phosphorylation and inhibits transcriptional regulation of SMYD3 target genes.EM127 slowly reduces methyltransferase activity over a long period of time.EM127 has potential anticancer activity and can be used to study SMYD3 positive tumors. EM127 has potential anticancer activity and can be used to study SMYD3 positive tumors.
Product Specifications
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
311.76
Molecular Formula
C14H18ClN3O3
Notes
Research use only, not for human use.
Receptor
Histone Methyltransferase | ERK
CAS Number
1886879-71-5
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7091119 Inquire
Recombinant Shigella flexneri Bifunctional protein aas (aas), partial
Ask
View Details 
MBS1109004-01 0.05 mg (E-Coli)
Recombinant Actinobacillus pleuropneumoniae serotype 7 DNA gyrase inhibitor YacG (yacG)
Ask
View Details MBS1109004-02 0.2 mg (E-Coli)
Recombinant Actinobacillus pleuropneumoniae serotype 7 DNA gyrase inhibitor YacG (yacG)
Ask
View Details