EM127
EM127 is a highly selective and potent covalent inhibitor of SMYD3 with a KD value of 13 μM.EM127 inhibits ERK1/2 phosphorylation and inhibits transcriptional regulation of SMYD3 target genes.EM127 slowly reduces methyltransferase activity over a long period of time.EM127 has potential anticancer activity and can be used to study SMYD3 positive tumors. EM127 has potential anticancer activity and can be used to study SMYD3 positive tumors.
Product Specifications
CAS Number
1886879-71-5
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
311.76
Molecular Formula
C14H18ClN3O3
Notes
Research use only, not for human use.
Receptor
Histone Methyltransferase | ERK
Available Sizes
Curated Selection
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