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DIF-3

DIF-3 is a chemical compound that acts by activating GSK-3β to facilitate the degradation of cyclin D1 and c-Myc, resulting in reduced expression levels of these proteins. In addition, DIF-3 inhibits Wnt/β-catenin signaling pathway-related proteins in DLD-1 cells. This compound exerts a potent antiproliferative effect on the HeLa human cervical cancer cell line by inducing cyclin D1 degradation and inhibiting cyclin D1 mRNA expression .

Product Specifications

CAS Number

113411-17-9

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

272.72

Molecular Formula

C13H17ClO4

Notes

Research use only, not for human use.

Receptor

Wnt/beta-catenin | GSK-3 | CDK

Available Sizes

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