(1S,2R) -Alicapistat
(1S,2R) -Alicapistat ((1S,2R) -ABT-957) is a highly efficient, orally active compound that selectively inhibits human calpains 1 and 2, showing promise for Alzheimer's disease (AD) therapy . It effectively addresses the metabolic liability associated with carbonyl reduction and demonstrates potent inhibition of calpain 1 with an IC50 value of 395 nM .
Product Specifications
CAS Number
2221010-57-5
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
433.5
Molecular Formula
C25H27N3O4
Notes
Research use only, not for human use.
Receptor
Cysteine Protease
Available Sizes
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