GA-017
GA-017 is a potent, selective inhibitor of LATS1 and LATS2 (large tumor suppressor kinase 1/2), exhibiting IC50 values of 4.10 and 3.92 nM, respectively. This compound simultaneously acts as an activator of cell proliferation by promoting YAP/TAZ activation and their nuclear translocation. Additionally, GA-017 enhances cell growth in 3D culture conditions and augments the ex vivo formation of mouse intestinal organoids .
Product Specifications
CAS Number
2351906-74-4
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
343.38
Molecular Formula
C18H21N3O4
Notes
Research use only, not for human use.
Receptor
Others
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