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AY 77

AY 77 (Unk-Cha-Chg-NH2) is a potent and selective PAR2 agonist. AY 77 showed selectivity for Ca2+ and ERK1/2 signaling (ec50 value of Ca2+ release was 40 nM and ec50 value of ERK1/2 phosphorylation was 2 μM) . AY 77 can promote migration of human breast cancer cells in vitro.

Product Specifications

CAS Number

1835734-92-3

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

404.5

Molecular Formula

C21H32N4O4

Notes

Research use only, not for human use.

Receptor

Protease-activated Receptor | Calcium Channel | ERK

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