5-Hydroxymethyl-2-deoxycytidine
5-Hydroxymethyl-2'-deoxycytidine is an oxidized derivative of 5-methyl-2'-deoxycytidine (5-mdC) in DNA, causing DNA damage reactions, chromosomal aberrations, replication fork damage, and loss of cell viability.5-Hydroxymethyl-2'-deoxycytidine is an oxidized derivative of 5-methyl-2'-deoxycytidine in DNA. Hydroxymethyl-2'-deoxycytidine replication fork instability is associated with the presence of poly (ADP-ribose) polymerase 1 (PARP1) on chromatin.
Product Specifications
CAS Number
7226-77-9
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
257.24
Molecular Formula
C10H15N3O5
Notes
Research use only, not for human use.
Receptor
PARP
Available Sizes
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