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CBR-470-1

CBR-470-1 is a potent inhibitor of glycolytic phosphoglycerate kinase 1 (PGK1) that activates NRF2 by increasing methylglyoxal levels. CBR-470-1 is a non-covalent Nrf2 activator with neuroprotective activity that protects SH-SY5Y neuronal cells from MPP+-induced cytotoxicity by activating the Keap1-Nrf2 cascade. cytotoxicity induced by MPP+.

Product Specifications

CAS Number

2416095-06-0

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

365.9

Molecular Formula

C14H20ClNO4S2

Notes

Research use only, not for human use.

Receptor

Nrf2

Available Sizes

Curated Selection

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