Taletrectinib free base
Taletrectinib free base (AB-106 free base) is a novel potent, selective and orally active ROS1/NTRK inhibitor.Taletrectinib free base has potent inhibitory effects on recombinant ROS1, NTRK1, NTRK2, and NTRK3, with IC50s of 0.207, 0.622, 2.28 and 0.98 nM, respectively, Taletrectinib free base also inhibited ROS1 G2032R and other Crizotinib-resistant ROS1 mutations.
Product Specifications
CAS Number
1505514-27-1
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
405.47
Molecular Formula
C23H24FN5O
Notes
Research use only, not for human use.
Receptor
ROS Kinase
Available Sizes
Curated Selection
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