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ML 209

ML-209 is an antagonist of retinoic acid receptor-related orphan receptor γt (RORγt; IC50= 1.1 μM in a reporter assay) .1It inhibits RORγt-induced transcription in HEK293T cells expressing the human receptor (IC50= 300 nM) . ML-209 inhibits RORγt-dependent differentiation of isolated na?ve cord blood human CD4+T cells into Th17 T helper cells.

Product Specifications

CAS Number

1334526-14-5

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

441.52

Molecular Formula

C25H31NO6

Notes

Research use only, not for human use.

Receptor

ROR

Available Sizes

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