ML 209
ML-209 is an antagonist of retinoic acid receptor-related orphan receptor γt (RORγt; IC50= 1.1 μM in a reporter assay) .1It inhibits RORγt-induced transcription in HEK293T cells expressing the human receptor (IC50= 300 nM) . ML-209 inhibits RORγt-dependent differentiation of isolated na?ve cord blood human CD4+T cells into Th17 T helper cells.
Product Specifications
CAS Number
1334526-14-5
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
441.52
Molecular Formula
C25H31NO6
Notes
Research use only, not for human use.
Receptor
ROR
Available Sizes
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