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(±) 8 (9) -EpETE

Eicosapentaenoic acid is converted to epoxyeicosatetraenoic acids (EpETEs) by several cytochrome P450 isoforms. The major product of this epoxygenase pathway, (±) 17 (18) -EpETE , relaxes vascular and airway smooth muscle by activating large conductance Ca2+-activated K+ (BKCa) channels by directly interacting with BKα channel subunits. (±) 8 (9) -EpETE is an epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo. The biological actions and physiological effects of this epoxide remain to be determined.

Product Specifications

CAS Number

851378-93-3

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

318.457

Molecular Formula

C20H30O3

Notes

Research use only, not for human use.

Receptor

Others

Available Sizes

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