(±) 8 (9) -EpETE
Eicosapentaenoic acid is converted to epoxyeicosatetraenoic acids (EpETEs) by several cytochrome P450 isoforms. The major product of this epoxygenase pathway, (±) 17 (18) -EpETE , relaxes vascular and airway smooth muscle by activating large conductance Ca2+-activated K+ (BKCa) channels by directly interacting with BKα channel subunits. (±) 8 (9) -EpETE is an epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo. The biological actions and physiological effects of this epoxide remain to be determined.
Product Specifications
CAS Number
851378-93-3
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
318.457
Molecular Formula
C20H30O3
Notes
Research use only, not for human use.
Receptor
Others
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