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Ac-FLTD-CMK

Ac-FLTD-CMK is an inhibitor derived from abscisicin D (GSDMDD) with specific inhibitory effects on inflammatory caspases. ac-FLTD-CMK showed inhibitory effects on caspases-1, caspases-4 and caspases-11 with IC50s of 46.7 nM, 1.49 μM and 329 nM, respectively. Ac-FLTD-CMK showed potency against caspases-1, caspases-4 and caspases-11, but not against apoptosis-associated caspase-3.

Product Specifications

CAS Number

2376255-48-8

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

569.05

Molecular Formula

C26H37ClN4O8

Notes

Research use only, not for human use.

Receptor

Caspase

Available Sizes

Curated Selection

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